Thomas married Mary Whitehead Greening in 1827. Mary (daughter of John Greening and Mary Whitehead) was born in 1811 in Sumter, SC; died on 16 May 1862 in Mansfield, Desoto Parish, LA. [Group Sheet] [Family Chart]

1. Mary Frances Guy was born on 1 Jan 1828 in Dallas, County, Al; died on 20 Aug 1913 in Mansfield, Desoto Parish, LA; was buried in Aug 1913 in Pegues-Stevenson Cemetery, Desoto Parish, LA.
2. Samuel Eldridge Guy was born on 14 Feb 1829 in Dallas, County, Al; died on 2 Mar 1887 in Mansfield, Desoto Parish, LA; was buried in Old Mansfield Cemetery, Desoto Parish, Louisana.
3. Elizabeth Ann Guy was born on 30 Sep 1830 in Dallas, County, Al; died on 14 Jul 1902 in Mansfield, Desoto Parish, LA; was buried in Old Mansfield Cemetery, Desoto Parish, Louisana.
4. Thomas Augustus Guy was born on 5 Aug 1833 in ,Dallas County, Alabama; died in 1904 in Mansfield, Desoto Parish, LA; was buried in 1904 in Old Mansfield Cemetery, Mansfield, LA.