| # | Children | Name | Born | Died | Father | Mother |
| 1 | | | b. Abt 1510 | d. DECEASED | John Macfarlane, 11th Baron of Arrochar 8th Clan Chief | 3rd wife Lady Helen Stewart |
| 2 | | | b. Abt 1513 | d. DECEASED | John Macfarlane, 11th Baron of Arrochar 8th Clan Chief | 3rd wife Lady Helen Stewart |
| 3 | | | b. Abt 1507 | d. 1547 | John Macfarlane, 11th Baron of Arrochar 8th Clan Chief | 2nd wife daughter of Herbert, Lord Herries |
| 4 | Yes | | b. Abt 1496 | d. 1544 | John Macfarlane, 11th Baron of Arrochar 8th Clan Chief | 1st wife daughter of James, Lord Hamilton |
| 5 | Yes | | b. Abt 1498 | d. 1544 | John Macfarlane, 11th Baron of Arrochar 8th Clan Chief | 1st wife daughter of James, Lord Hamilton |
| 6 | | | b. Abt 1500 | d. DECEASED | John Macfarlane, 11th Baron of Arrochar 8th Clan Chief | 1st wife daughter of James, Lord Hamilton |